Transplant Infectious Disease 2012-12-01

Fumagillin-induced aseptic meningoencephalitis in a kidney transplant recipient with microsporidiosis.

A Audemard, M L Le Bellec, L Carluer, S Dargère, R Verdon, C Castrale, T Lobbedez, B Hurault de Ligny

Index: Transpl. Infect. Dis. 14(6) , E147-9, (2012)

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Abstract

Microsporidiosis is an opportunistic infection in organ transplant recipients and patients with other cellular immunodeficiency. Fumagillin is an effective treatment against Enterocytozoon bieneusi, one of the two main species causing the microsporidiosis involved in human diseases. We report the first case, to our knowledge, of a probable drug-induced aseptic meningoencephalitis, after administration of fumagillin in a kidney transplant recipient with microsporidiosis.© 2012 John Wiley & Sons A/S.