A mild, clean, and simple synthesis of symmetrical carboxylic anhydrides from carboxylic acides using a polymer supported tosyl chloride

MAK Zarchi, BF Mirjalili, ZS Kahrizsangi…

Index: Zarchi, M. A. Karimi; Mirjalili; Kahrizsangi, Z. Shamsi; Tayefi Journal of the Iranian Chemical Society, 2010 , vol. 7, # 2 p. 455 - 460

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Citation Number: 11

Abstract

Abstract The use of polymeric reagents simplifies routine acylation of carboxylic acid because it eliminates the traditional purification. We describe the use of readily available cross-linked poly (4-vinylpyridine) supported tosyl chloride,[P 4 VP]. TsCl, in the suspended solution phase synthesis of symmetrical anhydrides from carboxylic acids in the presence of K 2 CO 3 in high yields and purity. The products can be obtained by filtration and ...