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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Design, synthesis and anticancer activity evaluation of diazepinomicin derivatives

Y Yu, J Wu, F Lei, L Chen, W Wan, L Hai…

Index: Letters in Drug Design and Discovery, , vol. 10, # 4 p. 369 - 373

Full Text: HTML

Citation Number: 4

Abstract

... 24a-e and 25a-h were conducted on human cancer cell lines HepG2 (hepatocellular liver carcinoma cell line), Lu-04 (lung cancer cell line) and Leu02 (human leukemia cell line) in vitro, meanwhile well known anticancer drugs Taxol and ... Letters in Drug Design & Discovery ...

 Related Synthetic Route
Toluene Structure

108-88-3

Toluene

~%

Anthranilic acid Structure

118-92-3

Anthranilic acid

4,8-Decadienoic acid, 2-acetyl-5,9-dimethyl-, ethyl ester, (E)- Structure

19894-78-1

4,8-Decadienoic...

~%

(2E,6E)-Farnesol Structure

106-28-5

(2E,6E)-Farnesol

N-(4-Chloro-2-nitrophenyl)acetamide Structure

881-51-6

N-(4-Chloro-2-n...

~%

Benzoicacid, 2-[(2-amino-4-chlorophenyl)amino]- Structure

67990-66-3

Benzoicacid, 2-...

4-Chloro-2-nitroaniline Structure

89-63-4

4-Chloro-2-nitr...

~%

Benzoicacid, 2-[(2-amino-4-chlorophenyl)amino]- Structure

67990-66-3

Benzoicacid, 2-...

Toluene Structure

108-88-3

Toluene

~%

Benzoicacid, 2-[(2-amino-4-chlorophenyl)amino]- Structure

67990-66-3

Benzoicacid, 2-...

2-Nitrotoluene Structure

88-72-2

2-Nitrotoluene

~%

Benzoicacid, 2-[(2-amino-4-chlorophenyl)amino]- Structure

67990-66-3

Benzoicacid, 2-...

2-Nitrobenzoic acid Structure

552-16-9

2-Nitrobenzoic acid

~%

Benzoicacid, 2-[(2-amino-4-chlorophenyl)amino]- Structure

67990-66-3

Benzoicacid, 2-...

2-Iodobenzoic acid Structure

88-67-5

2-Iodobenzoic acid

~%

Benzoicacid, 2-[(2-amino-4-chlorophenyl)amino]- Structure

67990-66-3

Benzoicacid, 2-...

4-Chloroaniline Structure

106-47-8

4-Chloroaniline

~%

Benzoicacid, 2-[(2-amino-4-chlorophenyl)amino]- Structure

67990-66-3

Benzoicacid, 2-...

4-Chloroacetanilide Structure

539-03-7

4-Chloroacetanilide

~%

Benzoicacid, 2-[(2-amino-4-chlorophenyl)amino]- Structure

67990-66-3

Benzoicacid, 2-...

Toluene Structure

108-88-3

Toluene

~%

2-Nitrobenzoic acid Structure

552-16-9

2-Nitrobenzoic acid

2-Anisidine Structure

90-04-0

2-Anisidine

~%

2-Methoxy-6-nitroaniline Structure

16554-45-3

2-Methoxy-6-nit...

2'-Methoxyacetanilide Structure

93-26-5

2'-Methoxyaceta...

~%

2-Methoxy-6-nitroaniline Structure

16554-45-3

2-Methoxy-6-nit...

Toluene Structure

108-88-3

Toluene

~%

2-Iodobenzoic acid Structure

88-67-5

2-Iodobenzoic acid

2-Nitrotoluene Structure

88-72-2

2-Nitrotoluene

~%

2-Iodobenzoic acid Structure

88-67-5

2-Iodobenzoic acid

2-Nitrobenzoic acid Structure

552-16-9

2-Nitrobenzoic acid

~%

2-Iodobenzoic acid Structure

88-67-5

2-Iodobenzoic acid

 Structure

74497-02-2

~%

2'-Nitroacetanilide Structure

552-32-9

2'-Nitroacetanilide

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Detail Synthetic Route


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