Sao Paulo Medical Journal 2010-10-01

Efficacy and safety of atypical antipsychotic drugs (quetiapine, risperidone, aripiprazole and paliperidone) compared with placebo or typical antipsychotic drugs for treating refractory schizophrenia: overview of systematic reviews.

Tamara Melnik, BernardoGarcia Soares, MariaEduardaDosSantos Puga, AlvaroNagib Atallah

Index: Sao. Paulo Med. J. 128(3) , 141-66, (2010)

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Abstract

According to some cohort studies, the prevalence of refractory schizophrenia (RS) is 20-40%. Our aim was to evaluate the effectiveness and safety of aripiprazole, paliperidone, quetiapine and risperidone for treating RS.