Chemical Communications 2012-01-07

A novel exonuclease III aided amplification method for sensitive nucleic acid detection based on single walled carbon nanotube induced quenching.

Hui Chen, Jiaqin Wang, Guohai Liang, Peng Zhang, Jilie Kong

Index: Chem. Commun. (Camb.) 48(2) , 269-71, (2012)

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Abstract

We describe herein a novel exonuclease III aided amplification method based on single walled carbon nanotube quenching (EASQ) for sensitive and convenient nucleic acid detection, which enabled 80-fold decrease of detection limit for HIV1 DNA assay compared with no target recycling.This journal is © The Royal Society of Chemistry 2012