Gan to kagaku ryoho. Cancer & chemotherapy 2013-05-01

[A case of recurrent colon cancer developed thrombosis in superior mesenteric vein after chemotherapy].

Hiroaki Furuyama, Hiroaki Fuji, Shinya Okumura, Tatsuhito Nishigori, Yoshio Kadokawa, Masato Kondo, Takafumi Machimoto, Yoshito Asao, Tsunehiro Yoshimura

Index: Gan To Kagaku Ryoho. 40(5) , 659-61, (2013)

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Abstract

A 48-year-old man was administered bevacizumab+FOLFOX for lymph node recurrence of colon cancer in the abdominal cavity, and developed serious thrombosis of the portal system after 6 courses of the chemotherapy. We discontinued it promptly and anticoagulant therapy with urokinase was started immediately, but a complete dissolution was not achieved. Preservation therapy using anticoagulants for a long duration was effective for controling the of clinical symptom of thrombosis. The result of 6 courses of chemotherapy was CR, and the effect continues today, without further treatment 2 years later.