Journal of Basic Microbiology 2012-08-01

Bioresolution of benzyl glycidyl ether using whole cells of Bacillus alcalophilus.

Neeraj Bala, Kirandeep Kaur, Swapandeep Singh Chimni, Harvinder Singh Saini, Shamsher Singh Kanwar

Index: J. Basic Microbiol. 52(4) , 383-9, (2012)

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Abstract

The incubation of whole Bacillus alcalophilus cells grown on a mineral supplemented medium (MSM) containing 1% (w/v) sucrose as carbon source, 1.2% (w/v) tryptone as nitrogen source at pH 6.5 and temperature 30 °C in 24 h kinetically resolved benzyl glycidyl ether (1 mg/ml) to provide (S)-benzyl glycidyl ether with 30% ee and (R)-3-benzyloxypropane-1,2-diol with 40% ee.Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.