Introduction. Reversible addition-fragmentation chain transfer (RAFT) 1, 2 polymerization and macromolecular architecture design by interchange of xanthates (MADIX) 3, 4 are the two of the youngest living radical polymerization (LRP) techniques. Like the two other main LRP techniques (transition-metal-mediated LRP, also known as atom transfer radical polymerization, ATRP, and nitroxide mediated polymerization, NMP), RAFT and MADIX ...