Eleven different planar hydroxy alkylated polyarenes 1–11 with different geometry, bulk and electronic characteristics were synthesised, and used for tethering to the 5′-phosphate of a 9-mer and a 18-mer DNA sequences through solid-phase synthesis. The 5′-polyarene- tethered 9-mers 30–40 were tested for their ability to form stable duplexes with four complementary target DNA-strands 25–28 of different length. The 5′-polyarene-tethered ...