Vaccine 2014-05-01

A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on generalized modules for membrane antigens (GMMA).

Oliver Koeberling, Emma Ispasanie, Julia Hauser, Omar Rossi, Gerd Pluschke, DominiqueA Caugant, Allan Saul, CalmanA MacLennan

Index: Vaccine 32(23) , 2688-95, (2014)

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Abstract

Neisseria meningitidis causes epidemics of meningitis in sub-Saharan Africa. These have mainly been caused by capsular group A strains, but W and X strains are increasingly contributing to the burden of disease. Therefore, an affordable vaccine that provides broad protection against meningococcal disease in sub-Saharan Africa is required.