Deutsche Medizinische Wochenschrift 2014-07-01

[Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options].

G J Molderings, J Homann, S Brettner, M Raithel, T Frieling

Index: Dtsch. Med. Wochenschr. 139(30) , 1523-34; quiz 1535-8, (2014)

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Abstract

In the present paper clinical phenotypes, pathogenetic relationships, and diagnostic algorithms as well as therapeutic concepts of/for systemic mast cell activation disease are reviewed. The reader should be able to recognize and diagnose a systemic mast cell activation disease, as well as to counsel a personalized drug therapy. In the case of chronic multisystem polymorbidity systemic mast cell activation disease should be considered as a differential diagnosis at an early stage. In most cases, specific, little invasive investigations allow diagnosing the disease and, hence, an appropriate therapy can be initiated. © Georg Thieme Verlag KG Stuttgart · New York.