Comparative Biochemistry and Physiology Part A: Physiology 1992-01-01

An in vitro gas equilibration method for determination of chemical partition coefficients in fish.

A D Hoffman, S L Bertelsen, M L Gargas

Index: Comp. Biochem. Physiol. A. Comp. Physiol. 101(1) , 47-51, (1992)

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Abstract

1. A gas equilibration method for the determination of in vitro chemical partition coefficients in mammals was adapted for use with fish. 2. In vitro blood: water and tissue: blood partition coefficients were determined for three chlorinated ethanes in rainbow trout (Oncorhynchus mykiss). 3. In vitro partition coefficients accurately predicted chemical concentrations in tissues of exposed trout.