Gan to kagaku ryoho. Cancer & chemotherapy 2013-06-01

[An autopsy of G-CSF-producing anaplastic carcinoma of the pancreas with impaired accumulation on FDG-PET after S-1 chemotherapy].

Shohei Ikeda, Kenji Okubo, Hiroaki Shibahara, Michihiko Narita, Kiyoshi Morita, Atsufumi Takeuchi, Hironobu Kanazawa, Takanori Ito, Daisaku Nishimura, Naoyuki Katada

Index: Gan To Kagaku Ryoho. 40(6) , 789-92, (2013)

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Abstract

This paper presents a woman in her 70's with G-CSF producing anaplastic carcinoma of the pancreas(Stage IVb)who underwent chemotherapy by S-1 alone. On FDG-PET after the first course, accumulation of FDG was impaired remarkably. After the second course, the patient died of carcinomatous pleuritis and peritonitis on the 88th day after initiation of treatment. G-CSF producing anaplastic carcinoma of the pancreas is extremely rare and there are no reports with regard to response evaluation by FDG-PET. Thus, this case has significant clinical value.