Artificial Cells, Nanomedicine and Biotechnology 2014-06-01

Schiff bases attached L-glutamine and L-asparagine: first investigation on antimutagenic and antimicrobial analyses.

Iffet Sakiyan, Mustafa Anar, Hatice Oğütcü, Guleray Agar, Nurşen Sarı

Index: Artif. Cells. Nanomed. Biotechnol. 42(3) , 199-204, (2014)

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Abstract

This study was conducted to evaluate the antimutagenic and antimicrobial activities of Schiff bases attached L-glutamine and L-asparagine. Antibacterial activities of the compounds against S. aureus, Sh. dys. typ 7, L. monocytogenes 4b, E. coli, S. typhi H, S. epidermis, Br. abortus, M. luteus, B. cereus, P. putida, and antifungal activity against Candida albicans were studied. These compounds were investigated for antimutagenic properties against Aflatoxin Bı (AFBı) using micronuclei (MN) assay in human lymphocyte cell culture in vitro. The protective role of these compounds against AFBı-induced MN is probably related to its doses.