New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-substituted thieno [2, 3-b] thiophene-2-sulfonamides and 5-substituted …

JD Prugh, GD Hartman, PJ Mallorga…

Index: Journal of Medicinal Chemistry, , vol. 34, # 6 p. 1805 - 1818

Full Text: HTML

Citation Number: 99

Abstract

... of the compound to concentrate in the iris plus ciliary body;I3 for sensitization liability in the guinea pig maximum sensi- tization test14 (GPMST); mutagenic liability in the Ames test;15 and pharmaceutical formulateability.16 At ... 1810 Journal of Medicinal Chemistry, 1991, Vol. ...

 Related Synthetic Route
dibromothiophene Structure

3140-93-0

dibromothiophene

Formylpiperidine Structure

2591-86-8

Formylpiperidine

~%

3-Bromo-2-thiophenecarbaldehyde Structure

930-96-1

3-Bromo-2-thiop...

2-PHENYL-5-OXAZOLONE Structure

5625-98-9

2-PHENYL-5-OXAZOLONE

~%

2-Morpholinoethanamine Structure

2038-03-1

2-Morpholinoeth...

3-Bromo-2-thiophenecarbaldehyde Structure

930-96-1

3-Bromo-2-thiop...

~%

THIENO[3,2-B]THIOPHENE-2-CARBALDEHYDE Structure

31486-86-9

THIENO[3,2-B]TH...

methyl 3-[2-(2-formylyhiophene-3-yl)]-3-thiapropionate Structure

1723-29-1

methyl 3-[2-(2-...

~%

THIENO[3,2-B]THIOPHENE-2-CARBALDEHYDE Structure

31486-86-9

THIENO[3,2-B]TH...

2-(3-bromothiophen-2-yl)-1,3-dioxolane Structure

56857-02-4

2-(3-bromothiop...

~%

THIENO[3,2-B]THIOPHENE-2-CARBALDEHYDE Structure

31486-86-9

THIENO[3,2-B]TH...

METHYL THIENO[3,2-B]THIOPHENE-2-CARBOXYLATE Structure

98800-10-3

METHYL THIENO[3...

~%

THIENO[3,2-B]THIOPHENE-2-CARBALDEHYDE Structure

31486-86-9

THIENO[3,2-B]TH...

methyl 3-(2-(2-dioxolanyl)thiophene-3-yl)-3-thiapropionate Structure

127025-33-6

methyl 3-(2-(2-...

~%

THIENO[3,2-B]THIOPHENE-2-CARBALDEHYDE Structure

31486-86-9

THIENO[3,2-B]TH...

3-Bromo-2-thiophenecarbaldehyde Structure

930-96-1

3-Bromo-2-thiop...

~%

METHYL THIENO[3,2-B]THIOPHENE-2-CARBOXYLATE Structure

98800-10-3

METHYL THIENO[3...

2-(3-bromothiophen-2-yl)-1,3-dioxolane Structure

56857-02-4

2-(3-bromothiop...

~%

METHYL THIENO[3,2-B]THIOPHENE-2-CARBOXYLATE Structure

98800-10-3

METHYL THIENO[3...

methyl 3-(2-(2-dioxolanyl)thiophene-3-yl)-3-thiapropionate Structure

127025-33-6

methyl 3-(2-(2-...

~%

METHYL THIENO[3,2-B]THIOPHENE-2-CARBOXYLATE Structure

98800-10-3

METHYL THIENO[3...


Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved