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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Cycloalkyl [b][1, 4] benzodiazepinoindoles are agonists at the human 5-HT 2C receptor

AL Sabb, RL Vogel, GS Welmaker, JE Sabalski…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 10 p. 2603 - 2607

Full Text: HTML

Citation Number: 36

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... a Chemical and Screening Sciences, Wyeth Research, CN 8000, Princeton, NJ 08543-8000, USA; b Wyeth Neuroscience, Wyeth Research, CN 8000, Princeton, NJ 08543-8000, USA. ...

 Related Synthetic Route
ethyl (2-aminobenzoyl)-L-alaninate Structure

769120-97-0

ethyl (2-aminob...

~%

(3S)-3-(PYRROLIDIN-1-YL)PYRROLIDINE Structure

104873-98-5

(3S)-3-(PYRROLI...

Isatoic anhydride Structure

118-48-9

Isatoic anhydride

~%

(3S)-3-(PYRROLIDIN-1-YL)PYRROLIDINE Structure

104873-98-5

(3S)-3-(PYRROLI...

7-Chloro-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione Structure

5177-39-9

7-Chloro-3,4-di...

~%

7-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine Structure

57756-37-3

7-Chloro-2,3,4,...

5-Chloroisatonic anhydride Structure

4743-17-3

5-Chloroisatoni...

~%

7-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine Structure

57756-37-3

7-Chloro-2,3,4,...

o-Amino-5-chlor-hippursaeureethylester Structure

58483-83-3

o-Amino-5-chlor...

~%

7-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine Structure

57756-37-3

7-Chloro-2,3,4,...

Isatoic anhydride Structure

118-48-9

Isatoic anhydride

~%

2,3,4,5-Tetrahydro-1H-1,4-benzodiazepine Structure

5946-39-4

2,3,4,5-Tetrahy...

(2-aminobenzoylamino)acetic acid ethyl ester Structure

5973-34-2

(2-aminobenzoyl...

~%

2,3,4,5-Tetrahydro-1H-1,4-benzodiazepine Structure

5946-39-4

2,3,4,5-Tetrahy...

Isatoic anhydride Structure

118-48-9

Isatoic anhydride

~%

4-Acetyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine Structure

57756-36-2

4-Acetyl-2,3,4,...

3,4-Dihydro-1H-1,4-benzodiazepine-2,5-dione Structure

5118-94-5

3,4-Dihydro-1H-...

~%

4-Acetyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine Structure

57756-36-2

4-Acetyl-2,3,4,...

(2-aminobenzoylamino)acetic acid ethyl ester Structure

5973-34-2

(2-aminobenzoyl...

~%

4-Acetyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine Structure

57756-36-2

4-Acetyl-2,3,4,...

7-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione Structure

422318-46-5

7-methyl-3,4-di...

~%

7-Methyl-2,3,4,5-tetrahydro-1hbenzo[e][1,4]diazepine Structure

422318-36-3

7-Methyl-2,3,4,...

6-Methyl-isatoic anhydride Structure

4692-99-3

6-Methyl-isatoi...

~%

7-Methyl-2,3,4,5-tetrahydro-1hbenzo[e][1,4]diazepine Structure

422318-36-3

7-Methyl-2,3,4,...

N/A Structure

769120-95-8

N/A

~%

7-Methyl-2,3,4,5-tetrahydro-1hbenzo[e][1,4]diazepine Structure

422318-36-3

7-Methyl-2,3,4,...

8-fluoro-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione Structure

620948-89-2

8-fluoro-3,4-di...

~%

8-Fluoro-2,3,4,5-tetrahydro-1hbenzo[e][1,4]diazepine Structure

620948-83-6

8-Fluoro-2,3,4,...

4-Fluoroisatoic anhydride Structure

321-50-6

4-Fluoroisatoic...

~%

8-Fluoro-2,3,4,5-tetrahydro-1hbenzo[e][1,4]diazepine Structure

620948-83-6

8-Fluoro-2,3,4,...

ethyl (2-amino-4-fluorobenzoyl)glycinate Structure

769120-96-9

ethyl (2-amino-...

~%

8-Fluoro-2,3,4,5-tetrahydro-1hbenzo[e][1,4]diazepine Structure

620948-83-6

8-Fluoro-2,3,4,...

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Detail Synthetic Route


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