Urology 2014-04-01

Late Ureteral Obstruction After Injection of Dextranomer/Hyaluronic Acid Copolymer

Samuel Christen, Mario Mendoza, Rita Gobet, Peter Bode, Daniel Weber

Index: Urology 83(4) , 920-2, (2014)

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Abstract

Various biological and artificial materials have been introduced for endoscopic treatment of vesicoureteral reflux. Over the past years, dextranomer combined with hyaluronic acid (Dx/Ha) has been established as the most commonly used tissue-augmenting substance for subureteral injection because of its biocompatibility. Nevertheless, the histopathologic analysis of failed Dx/Ha injections showed changes in consistency and volume of the deposit and granulomatous reactions of the adjacent tissue. We report a case of late-onset obstruction 2 years after the injection of Dx/Ha. In the current literature, this potential long-term complication is hardly mentioned.