3-Carbethoxy-4-hydroxy-7-bromoquinoline.-The intermediate ethyl a-carbethoxy-0-rn- bromoanilinoacrylate was obtained in 40% yield (45 9.) by allowing a mixture of 50 g. of m- bromoanilinel* and 63 g. of ethoxymethylenemalonic ester” to stand overnight. The resulting solid mass was twice recrystallized from a 1: 1 osolution of ether and ligroin; white needles, mp 70-71. This material, 40 g., was cyclized by refluxing in diphenyl ether according to ...
