Journal of Chromatography B 2011-01-01

Simultaneous determination of osthole, bergapten and isopimpinellin in rat plasma and tissues by liquid chromatography–tandem mass spectrometry

Jing Li, Bo Ma, Qi Zhang, Xiaojing Yang, Jingjing Sun, Bowen Tang, Guangbo Cui, Di Yao, Lei Liu, Guiying Gu, Jianwei Zhu, Ping Wei, Pingkai Ouyang

Index: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 970 , 77-85, (2014)

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Abstract

• Simultaneous determination of osthole, bergapten and isopimpinellin. • The validated method was applied to pharmacokinetic and tissue distribution. • Simultaneous analysis of three active compounds in gonad tissue was studied firstly