Journal of Chromatography B 2014-04-15

Determination of sitafloxacin in human plasma by liquid chromatography–tandem mass spectrometry method: Application to a pharmacokinetic study

Kai Huang, Jie Yang, Jing Zhang, Ying Ding, Lan Chen, Wen-Yan Xu, Xue-Jiao Xu, Ru Duan, Qing He

Index: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 957 , 36-40, (2014)

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Abstract

• An LC–MS/MS method has been developed for determining sitafloxacin in human plasma. • The method has some merits: high sensitivity, small sample volume and short runtime. • It is successfully applied to the pharmacokinetic study of sitafloxacin in human.