Tetrahedron

Claisen rearrangement/Baylis–Hillman reaction/ring-closing metathesis as bases for the construction of substituted cyanonaphthalenes

…, LY Chen, JY Tzeng, JC Tsai, PC Chi, SR Li, EC Wang

Index: Chen, Po-Yuan; Chen, Hsing-Ming; Chen, Liang-Yeu; Tzeng, Jing-Yu; Tsai, Jui-Chi; Chi, Ping-Cheng; Li, Sie-Rong; Wang, Eng-Chi Tetrahedron, 2007 , vol. 63, # 13 p. 2824 - 2828

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Citation Number: 29

Abstract

The present paper described how to establish a novel approach for various alkoxycyanonaphthalenes. It was started from isovanillin, and based on the Claisen rearrangement, O-alkylation, the Baylis–Hillman reaction, and ring-closing metathesis in sequence to produce the title compounds in good yield.