SnCl2-catalyzed three-component one-pot Mannich-type reaction: efficient synthesis of β-aminocarbonyl compounds

M Wang, ZG Song, X Wan, S Zhao

Index: Wang, Min; Song, Zhi-Guo; Wan, Xin; Zhao, Suang Monatshefte fur Chemie, 2009 , vol. 140, # 10 p. 1205 - 1208

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Citation Number: 15

Abstract

Abstract SnCl 2-catalyzed three-component one-pot Mannich reaction of acetophenone or p- chloroacetophenone with different aromatic aldehydes and aromatic amines in ethanol at ambient temperature gave the corresponding β-aminocarbonyl compounds in good to excellent yields. Four new compounds are reported for the first time. Graphical abstract