Russian journal of general chemistry

Synthesis of unsymmetrical β-arylaminoketones

NG Kozlov, LI Basalaeva

Index: Kozlov; Basalaeva Russian Journal of General Chemistry, 2004 , vol. 74, # 6 p. 926 - 932

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Citation Number: 9

Abstract

It follows from published data that b-arylamino- ketones are quite active local anesthetics [1]. They serve as starting materials in the synthesis of pyra- zolines [2] and compounds that exhibit bronchodilatat- ing and hypotensive properties [3]. As known, biolo- gical activity of compounds is closely related to their steric structure. Therewith, asymmetry is an indis- pensable attribute of most biomolecules [4]. ... The present work reports on the synthesis of amino- ketones ...