Russian journal of organic chemistry

Selenium-containing heterocycles. Synthesis and reactions of 2-amino-4, 5, 6, 7-tetrahydro-1-benzoselenophene-3-carbonitrile with anticipated biological activity

SH Abdel-Hafez

Index: Abdel-Hafez Russian Journal of Organic Chemistry, 2005 , vol. 41, # 3 p. 396 - 401

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Citation Number: 20

Abstract

Abstract Reaction of 2-amino-4, 5, 6, 7-tetrahydro-1-benzoselenophene-3-carbonitrile with ethylenediamine in the presence of a catalytic amount of carbon disulfide afforded 2-amino- 3-(4, 5-dihydro-1 H-imidazol-2-yl)-4, 5, 6, 7-tetrahydro-1-benzoselenophene. Cyclocondensation of the latter with triethyl orthoformate, benzaldehyde, and carbon disulfide gave tetracyclic imidazobenzoselenophenopyrimidine derivatives. Treatment of 2 ...