Canadian Journal of Chemistry

The Chromic Acid Oxidation of Aryl Trifluoromethyl Alcohols: Isotope and Substituent Effects

R Stewart, DG Lee

Index: Stewart,R.; Lee,D.G. Canadian Journal of Chemistry, 1964 , vol. 42, p. 439 - 446

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Citation Number: 33

Abstract

The mechanism of the chromic acid oxidation of eight aryltrmuoromethylcarbinols has been studied in acetic acid solution. Electron-donating substituents accelerate the reaction and a good correlation of rate with σ+ values has been found. The rho value is-1.01. Deuterium isotope effects for the oxidation of five of these compounds have been determined and the magnitude of the isotope effect has been found to correlate inversely with the ease of ...

1800-42-6

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