Synthesis and anti-inflammatory activity of imidazo [1, 2-a] pyridinyl/pyrazinyl benzamides and acetamides

…, K Sruthi, A Manjula, V Harinadha Babu…

Index: Hemasrilatha; Sruthi; Manjula; Harinadha Babu; Vittal Rao Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 7 p. 981 - 987

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Abstract

Abstract: The present study involves synthesis and determination of anti-inflammatory activity of a series of imidazo [1, 2-a] pyridinyl/pyrazinyl benzamides and acetamides. Sixteen new imidazo [1, 2-a] pyridinyl/pyrazinyl benzamides and acetamides have been prepared by the ring opening of 4-arylidene-2-methyl/phenyloxazolones with 2-amino azaheterocycles. All the compounds show significant anti-inflammatory activity. The anti- ...

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