A new, efficient and chemoselective one??pot protocol for synthesis of 4??arylidene??2??phenyl??5 (4H)??oxazolones from aryl aldehyde bisulfite adducts promoted by …

AR Khosropour, MM Khodaei…

Index: Khosropour, Ahmad R.; Khodaei, Mohammad M.; Hoseini Jomor, Seyed J. Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 3 p. 683 - 686

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Citation Number: 22

Abstract

4-Arylidene-2-phenyl-5 (4H) oxazolones (azlactones) and their derivatives, occupy an important place in the realm of biological and pharmaceutical sciences. They have served as versatile substrates to a variety of synthetic targets such as synthesis of peptides [1] and amino acids [2] or antitumor [3], antimicrobial [4], biosensor [5] or new heterocyclic compounds [6]. Hence, synthesis of this heterocyclic nucleus is of continuing interest. The ...