Analytical chemistry

Spectrophotometric determination of aspirin by trans acetylation of 4-aminophenol

KK Verma, A Jain

Index: Verma, Krishna K.; Jain, Archana Analytical Chemistry, 1986 , vol. 58, # 4 p. 821 - 824

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Citation Number: 21

Abstract

Aspirin transacetylates 4-amlnophenol, yielding acetamlnophen (N-acetyl-4-amlnophenoI), whlch can be determined by Its Oxidation to an orange-yellow product either by lodylbenzene In acetone when the absorbance is measured at 430 nm or by photometric titration with 2-lodylbenzoate In acetone-water medium at 444 nm. Sallcyllc acid, salicylamide, oxyphenbutazone, caffeine, and sodlum hydrogen carbonate do not ...