Friedel-Crafts acylation with N-(trifluoroacetyl)-. alpha.-amino acid chlorides. Application to the preparation of. beta.-arylalkylamines and 3-substituted 1, 2, 3, 4- …

JE Nordlander, MJ Payne, FG Njoroge…

Index: Nordlander, Eric J.; Payne, Mark J.; Njoroge, George F.; Balk, Michael A.; Laikos George D.; Vishwanath, Vasanth M. Journal of Organic Chemistry, 1984 , vol. 49, # 22 p. 4107 - 4111

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Citation Number: 52

Abstract

Results Friedel-Craft~ Acylations. The parent reaction of the study was conducted between N-(trifIuoroacety1) glycyl (3)(a) Zhao, Y.-F.; Xi, S.-K.; Tian, Y.. F; Song, A.-T. htrohdron htt. 1983, 24, 1617 (b) Rebek, J.; Shue, YKJ Am. Chem. Soc. 1980, 102, 5426.(c) Reifmrath, WC: Bsrtelli, DJ; Micklus, MJ; Fries, DS

~25%

~25%

~98%

~61%

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