e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Efficient Preparation of Biologically Important 1, 2-Amino Alcohols

P Gupta, A Rouf, BA Shah, D Mukherjee…

Index: Gupta, Pankaj; Rouf, Abdul; Shah, Bhahwal A.; Mukherjee, Debaraj; Taneja, Subhash C. Synthetic Communications, 2013 , vol. 43, # 4 p. 505 - 519

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Citation Number: 2

Abstract

The selective reduction of protected amino ketone derivatives is preferred because of their good stability. [ 8 8. Fujisawa , T. ; Hayashi , H. ; Kishioka , Y. Enantioselective synthesis of optically pure amino alcohol derivatives by yeast reduction . Chem. Lett. 1987 , 129 – 132 . [CrossRef], [Web of Science ®] View all references ] However, their precursors (amino ketones) are difficult to isolate as free amines because of the formation of Schiff bases. ...

2-(1-oxo-indan-2-yl)-isoindole-1,3-dione Structure

2-(1-oxo-indan-...

~%

2-Aminoindan-1-ol Structure

2-Aminoindan-1-ol

6-Bromindan-1-on Structure

6-Bromindan-1-on

~%

2-Aminoindan-1-ol Structure

2-Aminoindan-1-ol

2-(2-hydroxy-2-phenyl-ethyl)-isoindole-1,3-dione Structure

2-(2-hydroxy-2-...

~99%

phenylethanolamine Structure

phenylethanolamine

2-(2-hydroxypropyl)isoindole-1,3-dione Structure

2-(2-hydroxypro...

~38%

Amino-2-propanol Structure

Amino-2-propanol

2-(2-hydroxy-2-(4-methoxy-phenyl)-ethyl)-isoindole-1,3-dione Structure

2-(2-hydroxy-2-...

~91%

2-Amino-1-(4-methoxyphenyl)ethanol Structure

2-Amino-1-(4-me...

PTP inhibitor 1 Structure

PTP inhibitor 1

~%

2-Amino-1-(4-methoxyphenyl)ethanol Structure

2-Amino-1-(4-me...

2-[2-(4-methoxyphenyl)-2-oxoethyl]isoindole-1,3-dione Structure

2-[2-(4-methoxy...

~%

2-Amino-1-(4-methoxyphenyl)ethanol Structure

2-Amino-1-(4-me...

N-Acetonylphthalimide Structure

N-Acetonylphtha...

~93%

2-(2-hydroxypropyl)isoindole-1,3-dione Structure

2-(2-hydroxypro...

Potassium phthalimide Structure

Potassium phtha...

~%

2-(2-hydroxypropyl)isoindole-1,3-dione Structure

2-(2-hydroxypro...

Potassium phthalimide Structure

Potassium phtha...

3-Bromo-2-butanone Structure

3-Bromo-2-butanone

~98%

2-(1-Methyl-2-oxopropyl)-1H-isoindole-1,3-(2H)-dione Structure

2-(1-Methyl-2-o...

2-bromo-cyclo-hexanone Structure

2-bromo-cyclo-h...

Potassium phthalimide Structure

Potassium phtha...

~95%

2-(2-Oxocyclohexyl)-1H-isoindole-1,3(2H)-dione Structure

2-(2-Oxocyclohe...

Potassium phthalimide Structure

Potassium phtha...

2-Bromoacetophenone Structure

2-Bromoacetophenone

~95%

1H-Isoindole-1,3(2H)-dione,2-(2-oxo-2-phenylethyl)- Structure

1H-Isoindole-1,...

2-(2-hydroxy-2-p-tolyl-ethyl)-isoindole-1,3-dione Structure

2-(2-hydroxy-2-...

~92%

2-Amino-1-(4-methylphenyl)ethanol Structure

2-Amino-1-(4-me...

2-bromo-4'-methylacetophenone Structure

2-bromo-4'-meth...

~%

2-Amino-1-(4-methylphenyl)ethanol Structure

2-Amino-1-(4-me...

Potassium phthalimide Structure

Potassium phtha...

PTP inhibitor 1 Structure

PTP inhibitor 1

~96%

2-[2-(4-methoxyphenyl)-2-oxoethyl]isoindole-1,3-dione Structure

2-[2-(4-methoxy...

1H-Isoindole-1,3(2H)-dione,2-(2-hydroxycyclohexyl)- Structure

1H-Isoindole-1,...

~63%

(R)-2-Aminocyclohenanol Structure

(R)-2-Aminocycl...

N/A Structure

~95%

2-Amino-1-(4-nitrophenyl)ethanol Structure

2-Amino-1-(4-ni...

p-nitrophenacyl bromide Structure

p-nitrophenacyl...

~%

2-Amino-1-(4-nitrophenyl)ethanol Structure

2-Amino-1-(4-ni...

2-[2-(4-nitro-phenyl)-2-oxo-ethyl]-isoindole-1,3-dione Structure

2-[2-(4-nitro-p...

~%

2-Amino-1-(4-nitrophenyl)ethanol Structure

2-Amino-1-(4-ni...

2-[2-(4-fluoro-phenyl)-2-hydroxy-ethyl]-isoindole-1,3-dione Structure

2-[2-(4-fluoro-...

~93%

2-Amino-1-(4-fluorophenyl)ethanol Structure

2-Amino-1-(4-fl...

Studies on the Syntheses of Heterocyclic Compounds. CLIX. Th...

[Kametani,T. et al. Chemical and Pharmaceutical Bulletin, 1966 , vol. 14, p. 1408 - 1413]

Synthese von cis??und trans??2??Amino??indanol

[Rimek,H.-J. et al. Justus Liebigs Annalen der Chemie, 1969 , vol. 725, p. 116 - 123]

Synthese von cis??und trans??2??Amino??indanol

[Rimek,H.-J. et al. Justus Liebigs Annalen der Chemie, 1969 , vol. 725, p. 116 - 123]