Tetrahedron

Chemical fixation of CO 2: efficient synthesis of quinazoline-2, 4 (1H, 3H)-diones catalyzed by guanidines under solvent-free conditions

J Gao, LN He, CX Miao, S Chanfreau

Index: Gao, Jian; He, Liang-Nian; Miao, Cheng-Xia; Chanfreau, Sebastien Tetrahedron, 2010 , vol. 66, # 23 p. 4063 - 4067

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Citation Number: 57

Abstract

Guanidines were proved to be efficient catalysts for the chemical fixation of carbon dioxide with 2-aminobenzonitriles under solvent-free conditions. Notably, the catalysts with low loading worked well for a variety of 2-aminobenzonitriles. As a result, quinazoline-2, 4 (1H, 3H)-diones by employing present protocol were obtained in good yields under mild conditions. This process represents an alternative approach for the greener chemical ...