Synthesis, anticancer activities and molecular modeling studies of novel indole retinoid derivatives

…, E Dayanc, R Cetin-Atalay, E Buyukbingol

Index: Ates-Alagoz; Buyukbingol; Buyukbingol, Erdem Pharmazie, 2005 , vol. 60, # 9 p. 643 - 647

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Citation Number: 12

Abstract

In this study, novel (E)-3-(5-substituted-1H-indol-3-yl)-1-(5, 5, 8, 8-tetramethyl-5, 6, 7, 8- tetrahydronaphthalen-2-yl) prop-2-en-1-one (5 (a–e)) derivatives were synthesized and their anticancer effects were determined in vitro. Novel indole retinoid compounds except 5e