Betulin Derivatives Effectively Suppress Inflammation in Vitro and in Vivo

…, S Alakurtti, VM Moreira, J Yli-Kauhaluoma…

Index: Haavikko, Raisa; Nasereddin, Abedelmajeed; Sacerdoti-Sierra, Nina; Kopelyanskiy, Dmitry; Alakurtti, Sami; Tikka, Mari; Jaffe, Charles L.; Yli-Kauhaluoma, Jari MedChemComm, 2014 , vol. 5, # 4 p. 445 - 451

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Citation Number: 2

Abstract

Betulin is a pharmacologically active triterpenoid found in the bark of the birch tree (Betula sp. L.). Betulin and betulinic acid are structurally related to anti-inflammatory steroids, but little is known about their potential anti-inflammatory properties. In the present study, the