Structure–activity relationships of neuritogenic gentiside derivatives

…, L Gao, G Wang, Y Qu, L Xiang, L Chen, Y Hu…

Index: Luo, Yan; Sun, Kaiyue; Li, Lin; Gao, Lijuan; Wang, Guangfa; Qu, Yuan; Xiang, Lan; Chen, Ling; Hu, Yongzhou; Qi, Jianhua ChemMedChem, 2011 , vol. 6, # 11 p. 1986 - 1989

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Citation Number: 12

Abstract

Neurotrophic factors are target-derived peptides that play an important role in the development and survival of responsive neuronal populations. Nerve growth factor (NGF), one of the most important neurotrophic factors, is essential for neuronal differentiation, growth, survival, function maintenance, and prevention of aging in the central and peripheral systems.[1, 2] However, because of its large molecular size and hydrophilic properties, ...