Iron promoted conjugate addition: implication of the six-centered mechanism based on the isolation of the iron-enolate intermediate

…, T Hatakeyama, M Nakamura, H Nagashima

Index: Noda, Daisuke; Sunada, Yusuke; Hatakeyama, Takuji; Nakamura, Masaharu; Nagashima, Hideo Chemical Communications, 2012 , vol. 48, # 100 p. 12231 - 12233

Full Text: HTML

Citation Number: 2

Abstract

Treatment of (η1-mesityl) 2Fe (κ2-TMEDA)(1′) with an α, β-unsaturated carbonyl compound results in 1, 4-addition of the mesityl group to give an iron enolate 3 quantitatively. The Z-configuration of the enolate suggested the six-centered mechanism for the conjugate addition.