Synthesis of 1H??pyrazino [1, 2??a] pyrido [2, 3??e] pyrazine and 2H??Pyrano [2, 3??b] pyrido [2, 3??e] pyrazine Derivatives

F Savelli, A Boido, G Damonte

Index: Savelli, Francesco; Boido, Alessandro; Damonte, Gianluca Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 6 p. 1737 - 1742

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Citation Number: 10

Abstract

Abstract With a continuing interest on heteropolycyclic structures which may show biological activities, we synthesized new tricyclic derivatives in which the pyridopyrazine skeleton is fused with pyrazine 7 and 8, B, n= 1. However, the initial design of obtaining also the cyclohomologous structure B (n= 2) produced instead a pyranopyridopyrazine derivative 11. Thus during the attempt to prepare a pyridodiazepine intermediate, beside a very small ...