Racemic and diastereoselective construction of indole alkaloids under solvent-and catalyst-free microwave-assisted Pictet–Spengler condensation

…, B Deprez, G Laconde, R Deprez-Poulain

Index: Jida, Mouhamad; Soueidan, Olivier-Mohamad; Deprez, Benoit; Laconde, Guillaume; Deprez-Poulain, Rebecca Green Chemistry, 2012 , vol. 14, # 4 p. 909 - 911

Full Text: HTML

Citation Number: 13

Abstract

An environment-friendly high-yielding method for the racemic and asymmetric diastereoselective preparation of indole alkaloids via Pictet–Spengler reaction is reported. The reaction proceeds with short reaction times under solvent-free and microwave- irradiation conditions.