Synthesis and Pharmacological Evaluation of α, α-Disubstituted Derivatives of Phenylacetamide and 1-Naphthylacetamide

S Casadio, G Pala, T Bruzzese…

Index: Casadio,S. et al. Journal of Medicinal Chemistry, 1965 , vol. 8, p. 594 - 598

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Citation Number: 4

Abstract

-_ ba A= ethyl acetate, B= benzene, C= cyclohexane, E:= petroleum ether (bp 40-70"), H= hexane, L= ligroin (bp 75-120"). WB Wheatley, WF Xinor, W. 31. Byrd, WE Fitzgibbon, Jr., 11. E. Speeter, LC Cheney, and SB Binkley [J. Org. Chem., 19, e Prepared as the dipicrate by b4. Borovicka and 0 PAJ Janssen, D. Zizkovic, and P. Demoen [J. Am. Chem. Soc., 794 (1954)] reported mp 95-96.5*, yield 73y0. AI. Protiva, Chem. Listy, 51, 2118 (1957). 77, ...