Facile syntheses of C-6 azidopurine ribonucleosides and 2′-deoxyribonucleosides have been developed. For silyl-and acetyl-protected as well as unprotected nucleosides, access to the azido derivatives could be readily attained via displacement of BtO− from the O 6- (benzotriazol-1-yl) inosine nucleosides by azide anion. Use of diphenylphosphoryl azide/DBU as a simple route to the acetyl-protected azido nucleosides was also evaluated ...
