Alkaloid cardenolides

IF Makarovich, LV Ivanov, YI Khadzhai…

Index: Makarovich, I. F.; Ivanov, L. V.; Khadzhai, Ya. I.; Belokon', V. F.; Pavlova, V. V.; et al. Chemistry of Natural Compounds, 1985 , vol. 21, # 2 p. 224 - 228 Khimiya Prirodnykh Soedinenii, 1985 , # 2 p. 239 - 244

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Abstract

Abstract New alkaloid cardenolides have been synthesized and their biological activity has been studied. It has been established that ajmalinocardenolides possess cardiotonic and antiarrhythmic activity with a low or moderate toxicity, while cardenolides derivatives of hyoscyamine and of scopolamine have proved to be highly toxic compounds. Using fluorescent probes it has been shown that the ajmalinocardenolides are sorbed fairly ...