Host-guest complexation. 25. Effects of substituents on the complexing properties of chorands

…, GM Lein, H Nakamura, DJ Cram

Index: Bell, Thomas W.; Lein, George M.; Nakamura, Hideo; Cram, Donald J. Journal of Organic Chemistry, 1983 , vol. 48, # 24 p. 4728 - 4734

Full Text: HTML

Citation Number: 14

Abstract

Results We have reportedz3 the synthesis of 4, 5, 15, 16-bis (18-crown-6)[2.2] paracyclophane (1) 24 from 3-(morpholino-methyl)-6-methylcatechol (Scheme I). This host, which contains two 18-crown-6 rings annelated to two different benzene rings of [2.2] paracyclophane, was prepared by dimerization of p-phenylene-18-crown-6, which was produced by a Hoffman elimination reaction, as shown. Nuclear magnetic resonance ...