Helvetica Chimica Acta

Regiospecific Acylation, Alkylation, and Aldol Condensation using magnesium enolates resulting from the conjugate addition of grignard reagents to α, β??unsaturated …

F Näf, R Decorzant

Index: Naef,F.; Decorzant,R. Helvetica Chimica Acta, 1974 , vol. 57, p. 1317 - 1327

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Citation Number: 39

Abstract

Abstract The magnesium 3, 3-dimethylcyclohex-1-enolate 1i, formed in the copper catalyzed addition of methylmagnesium iodide to 3-methylcyclohex-2-enone, has been subjected to regiospecific electrophilic reactions such as acylation, alkylation, and aldol condensation in order to find a new access to the damascones, ionones and carotenoids. By way of illustration a new synthesis of γ-damascone is described.

SUR LA DOUBLE ÉNOLISATION DE LA DIMÉTHYL-3, 3 CYCLOHEXANONE

[Champagne,J. et al. Canadian Journal of Chemistry, 1964 , vol. 42, p. 212 - 222]

. alpha.-Halocarbonyl compounds. II. Position-specific prepa...

[Stotter,P.L.; Hill,K.A. Journal of Organic Chemistry, 1973 , vol. 38, # 14 p. 2576 - 2578]

The chemistry of carbanions. 29. The nature of the enolate f...

[House,H.O.; Wilkins,J.M. Journal of Organic Chemistry, 1976 , vol. 41, # 25 p. 4031 - 4033]

Der Reflex??Effekt, VII

[Duerr,H. et al. Chemische Berichte, 1965 , vol. 98, p. 1858 - 1878]