Tetrahedron Letters

Lewis acid-mediated nucleophilic reaction of 2-alkoxychromanes with silyl enol ethers

J Cossy, H Rakotoarisoa, P Kahn, JR Desmurs

Index: Cossy; Rakotoarisoa; Kahn; Desmurs Tetrahedron Letters, 2000 , vol. 41, # 37 p. 7203 - 7205

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Citation Number: 12

Abstract

2H-1-Benzopyrans (2H-chromenes) and 3,4-dihydro-2H-1-benzopyrans (chromanes) are important classes of oxygenated heterocyclic compounds 1 that have attracted much synthetic interest because of the biological activity 2. and 3. of naturally occurring representatives. In the course of our work on the synthesis of therapeutically valuable compounds with antioxidizing properties, we needed to access chromanes bearing various 2-oxoalkyl groups at the C-2 ...