Journal of Medicinal Chemistry

Central Nervous System Depressants--II. 4-Allyloxy-3, 5-dialkylbenzoic Acids and Derivatives

RB Moffett, PH Seay

Index: Moffett,R.B.; Seay,P.H. J. Med. Pharm. Chem., 1960 , vol. 2, p. 201 - 212

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Citation Number: 2

Abstract

The high activity of 4-allyloxy-3, 5-dipropylbenzoic acid and certain of its derivatives (I) in increasing the sleeping time of mice given small doses of hexobarbital1 has encouraged us to prepare a number of analogues in which methyl, ethyl, or isopropyl substituents replace the two propyl groups (11). In general these

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