Aryloxyalkylamines, N-arylethylenediamines, and related compounds as anorectic agents

…, RS Shadbolt, GR Brown, A Ashford…

Index: Shadbolt; Sharpe; Brown; Ashford; Ross Journal of medicinal chemistry, 1971 , vol. 14, # 9 p. 836 - 842

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Citation Number: 2

Abstract

Most'anorectic drugs have associated undesirable propert'ies such as CXS stimulation, euphoria, a, ddictiveness, and hypert'ension. A considerable number of modifications have been made to the amphetamine structure with a view to reducing it's stimulant properties while retaining anorexigenic activity. The most successful compound of this type is t, he N- ethyl-m-trifluoromethyl derivative, fenfluramine. 2 Some I-phenoxy-2-propylamine ...