Palladium??catalyzed furylation and thienylation of activated alkenes with 2??furoyl chloride and 2??thenoyl chloride

A Kasahara, T Izumi, T Ogihara

Index: Kasahara, Akira; Izumi, Taeko; Ogihara, Takao Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 597 - 599

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Citation Number: 12

Abstract

Abstract 2-Furoyl or 2-thenoyl chlorides readily react with activated alkenes in the presence of a tertiary amine and a catalytic amount of palladium (II) acetate to give 2-furylated or 2- thienylated alkenes. Under similar conditions, 2-benzofuroyl chloride undergoes facile alkenylation to produce 2-alkenylated benzofurans. The reaction involves a highly efficient decarbonylation of furoyl or thenoyl-palladium species.