The thiazole N-oxides are a poorly studied class of compounds. 2-Aminothiazole 3-oxides can be obtained by reductive cyclization of o-thiocyanatonitrobenzene [1], and also by reaction of α-chloroximes with barium thiocyanate [2]. At the same time thiocyanation of aromatic amines is widely used in the synthesis of fused 2-aminothiazoles. Thiocyanation of heterocyclic amines is usually carried out with thiocyanogen formed in situ by treating a ...
![2-amino-4H-[1,3]thiazolo[4,5-d]pyrimidine-5,7-dione Structure](https://image.chemsrc.com/caspic/011/30161-91-2.png)