Synlett

Synthesis and Characterization of [1] Benzopyrano [4, 3-d][1, 3] benzooxazocin-13-one and its Derivatives

JF Wang, YX Liao, PY Kuo, YH Gau, DY Yang

Index: Wang, Jen-Fei; Liao, Yuan-Xiu; Kuo, Pei-Yu; Gau, Yung-Her; Yang, Ding-Yah Synlett, 2006 , # 17 p. 2791 - 2794

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Citation Number: 18

Abstract

Abstract This work describes the efficient synthesis of functionalized cleft molecules 6, 6a, 16, 16a, 17, 19 and 20 derived from benzopyrano [4, 3-d][1, 3] benzooxazocin-13-one. X-ray crystal structure analysis of compounds 6a and 16a revealed that the cleft angles of the planes of the benzopyran moiety and the p-methoxybenzene ring are 109.4 and 108.6, respectively. The conformation of the aromatic ring at the bridgehead of 16, 16a and 20 is ...