Chinese Chemical Letters

A clean and efficient cyclocondensation to pyrido [2, 3-d] pyrimidine derivatives in aqueous media

R Baharfar, R Azimi

Index: Baharfar, Robabeh; Azimi, Razieh Chinese Chemical Letters, 2011 , vol. 22, # 10 p. 1183 - 1186

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Citation Number: 10

Abstract

A series of pyrido [2, 3-d] pyrimidine derivatives were easily constructed by cyclocondensation reactions of 6-aminouracils or 6-aminothiouracil with α, β-unsaturated carbonyl compounds (aldehyde, ketone and ester) possessing a leaving group on the β position, in H2O under reflux conditions.