Reactivity of Thioaldehyde: Cyclization Reaction of 6-Amino-1, 3-dimethyl-5-thioformyluracil with Enamines into Pyrido [2, 3-d] pyrimidine-2, 4-(1 H, 3 H)-diones

K Hirota, K Kubo, H Sajiki, Y Kitade…

Index: Hirota, Kosaku; Kubo, Keiko; Sajiki, Hironao; Kitade, Yukio; Sako, Magoichi; Maki, Yoshifumi Journal of Organic Chemistry, 1997 , vol. 62, # 9 p. 2999 - 3001

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Citation Number: 24

Abstract

Until quite recently investigation of the chemical properties of monomeric thioaldehydes was considered difficult because of their extreme instability. 1 Although two types of stable monomeric thioaldehydes are known in literature to be kinetically stabilized2, 3 or thermodynamically stabilized compounds, 4, 5 only a few reports have appeared concerning the reactivities of stable thioaldehydes. 3, 5, 6 We recently reported5c the synthesis and ...